![]() ![]() sakazakii to determine the protective effect of maternal immunity on the offspring. Three days after birth, the progeny were challenged with C. In this study, GroEL and OmpX were recombinantly expressed in Escherichia coli and purified as immunogens to immunize pregnant rats. ![]() sakazakii (GroEL and OmpX) exhibited high expression levels and elicited strong immune reactions, suggesting their potential as vaccine candidates. Previous studies showed that two proteins of C. sakazakii, it is considered that maternal immunity can enhance the protection of newborns. Since infants and young children are the main target group of C. Preventing infection by this pathogen is significant to the health of newborns. 2Tianjin Key Laboratory of Food Science and Health, School of Medicine, Nankai University, Tianjin, ChinaĬronobacter sakazakii is a food-borne pathogen carried in milk powder that can cause severe bacteremia, enterocolitis, and meningitis in newborns, which can lead to death of newborns. ![]()
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